Heart Failure

Heart Failure

Heart failure (HF), often referred to as congestive heart failure (CHF), occurs when the heart is unable to provide enough blood pressure to perfuse all of the bodies tissues effectively.  The cardiac insufficiency results in a sequalae of symptoms including shortness of breath, lethargy, and fluid accumulation in lower extremities.  Renal complications are often the result of diuretics prescribed to reduce fluid accumulation.

Common causes of heart failure include coronary artery disease, a previous myocardial infarction, high blood pressure, atrial fibrillation, valvular heart disease, excess alcohol use, infection, and cardiomyopathy of an unknown cause. 

Due to the complexity of heart failure there are multiple ways to measure or characterize the progression of the disease.  This include echocardiography, measurement of blood pressure, central venous pressure pulmonary artery pressure, left and right ventricular pressures and measuring cardiac dimensions.

Animal models used to study heart failure include mice, rats, rabbits and dogs.  Models are generated by several means, including, genetic selection, induced hypertension and electrical pacing of the heart.

DSI has solutions for capturing and analyzing bioelectrical and pressure measurements, plus hardwired solutions capable of combining telemetry with other systems such as cardiac dimension measurements.



Heart Failure articles citing DSI in Google Scholar

DSI offers a comprehensive line of telemetry implants capable of measuring pressure endpoints in species ranging from mice to swine. 

Learn more about the pressure sensing implants available from DSI.

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Ponemah software is trusted by hypertension researchers around the world to reliably and accurately acquire and analyze physiologic endpoints.

Learn more about Ponemah software from DSI.

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DSI's digital signal conditioners allow you to collect a wide array of physiologic endpoints, with signal processing that is best in class. Researchers can also integrate hardwired signals with telemetry signals, for even more study flexibility.

Learn more about digital signal conditioners from DSI.

Signal conditioners and amplifiers for preclinical research.