Infectious Disease

Scientific Overview of Infectious Disease

Increasing world populations and ease of international travel are driving the necessity for better preparedness to protect the public from infectious disease outbreaks. Infectious diseases are caused by pathogenic microorganisms such as bacteria, viruses, parasites or fungi. The U.S. government and many other governments and organizations around the world are engaged to help reduce the prevalence and incidence of these diseases by increasing treatment options.

Basic and applied research methodologies evaluate physiologic changes associated with infections and often include assessment of physiologic parameters or biomarkers such as temperature, fever, heart rate and heart rate variability.

Wireless, implantable telemetry is a proven technology designed for monitoring and collecting data from conscious, freely moving laboratory animals to mimic clinical scenarios determining desirable therapeutic effect.

When comparing diseases in animals with diseases in humans, researchers consider additional information such as time to onset of disease/condition, progression of disease and signs and symptoms of the disease. Physiologic changes lead to characterization of triggers that identify the optimal time for intervention for potential treatment regimens.  


Infectious Disease articles citing DSI in Google Scholar

PhysioTel Digital large animal implants
DSI offers several different implant combinations to measure different parameters including pressure, biopotentials, temperature and activity. 

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L21 Implant

Ponemah Remote Notification
Convenient, automated alerts for subject-level and system-level conditions. Continuous physiologic monitoring should not need your undivided attention. Avoid unnecessary entrance into BSL environments to check on your studies.  Remote Notification saves you time and provides peace of mind by monitoring subject health and system functionality, notifying you when necessary.
Learn more about the Ponemah Remote Notification software feature
Remote Notification Email

PhysioTel large animal respiratory implant
This first-of-its-kind device, the D70-PCTR, is a versatile option for researchers with a need to monitor a pressure, biopotential, temperature, respiratory volume,  respiration rate and activity.

Learn more about the PhysioTel large animal respiratory implant

Buxco respiratory exposure systems
DSI’s Buxco Mass Dosing Chambers are used to expose multiple subjects to an aerosol or gas when general dosing can be tolerated. For precise nose-only exposures, use the Inhalation Tower system.

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Mass Dosing system

Data analysis and report generation services
DSI delivers high-quality, customized, comprehensive reports for evaluation of: hemodynamics, heart rate variability, ECG interval quantification, arrhythmia detection, seizure detection, sleep scoring, blood pressure, respiration, temperature and activity that change from study to study and subject to subject. 

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Pre-implantation services
The choice is yours: Surgeries performed at your location on your test subjects, or Pre-implanted animals are delivered to your location. 

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Buxco inhalation dosing tower
For use with small animals, inhalation dosing towers ensure that simultaneous exposure of compounds or gases to the lungs of rodents is well controlled, consistent, and defined.

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